Our goal is to provide information that covers all the important aspects of this type cancer including diagnosis, treatment and what you need to know about finding a lawyer or attorney for your case if necessary.
For additional pictures and information, click here or on the picture below
What is Mesothelioma (Asbestos Cancer)?
It is a form of cancer in which malignant (cancerous) cells are found in the mesothelium which is a protective sac that covers most of the body's internal organs. Generally, most individuals who develop this cancer have worked on jobs or lived in apartments or buildings where asbestos particles were inhaled.
Asbestos cancer is when the mesothelium lining becomes abnormal and grows uncontrollably causing pain. This can be benign or malignant. The malignant form of the cancer will damage the tissue of the organ it resides on and possibly invade other organs. Most cases of mesothelioma are either pleural or peritoneal. the Most cases of begin in the pleura or peritoneum.
Mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women.
This site is dedicated to providing advice that can help those with questions concerning asbestos cancer.
Sunday, February 19, 2006
Pericardial Mesothelioma Treatment
Pericardial Mesothelioma Treatment by William Johnston
Pericardial Mesothelioma is an extremely difficult cancer to treat and presently, all treatment methods used have a poor success rate. The chances of a patient's survival depend largely on how early and how aggressively the cancer is treated. If pericardial mesothelioma is treated when it has fully matured and developed then the chances of survival are very slim and the prognosis for a patient could be only a couple of months. The latency period of pericardial mesothelioma (30 - 50 years), and its symptoms which are ordinary of other more common diseases such as pneumonia, make it extremely difficult to diagnose and therefore difficult to treat in its early stages. In this way, a lot of pericardial mesothelioma treatments do not aim to cure patients but instead focus on reducing the symptoms.
Before a patient is treated, a doctor will evaluate him or her, and afterwards decide which treatment method is most suitable for the patient's situation. The patient's age, medical history, general well being and even weight are taken into account before the doctor will decide which of the three treatments are most appropriate. These treatments are surgery, chemotherapy and radiation therapy.
Surgery
There are two different types of surgery that can be used one of which is called aggressive surgery. This is the most dangerous of all the treatment methods available and only the fittest of people are deemed strong enough to undergo this. Aggressive surgery consists of removing large chunks of cancerous cells from inside the patient. This is extremely dangerous in the case of pericardial mesothelioma seeing as the cancerous cells are in extremely close proximity to vital organs such as the heart and lungs. Extremely skilled surgeons are needed to perform this operation.
The second type of surgery is palliative procedures and this type of surgery is used only for the purpose of reducing the symptoms of the cancer. Palliative procedures are performed when pericardial mesothelioma is in its latest stages and is practically impossible to cure.
Chemotherapy
Chemotherapy is the most well known cure of cancers and involves using drugs to kill of cancerous cells. However, many of the drugs used do not have a high success rate although researchers are discovering new combinations of drugs that work more effectively. Many pharmaceutical companies are also endeavouring to find new drugs. Researchers predict that they will soon discover a drug with a significantly improved success rate.
Radiation Therapy
This form of treatment uses doses of radiation to kill cancerous cells. However, in the case of pericardial mesothelioma this is extremely difficult because as well as damaging cancerous cells, the radiation also damages vital organs such as the heart and lungs. This makes using radiation therapy most effectively extremely difficult. The dose of radiation is usually too weak to make a significant impact on curing pericardial mesothelioma.
Dual Therapy
Dual therapy is just a combination of surgery, chemotherapy and radiation therapy. This consists of using surgery to remove the majority of the cancer cells and then using chemotherapy and radiation therapy to kill off any remaining cells. This has proved to be an effective treatment method however also very dangerous. Only the fittest young people are able to undergo this treatment.
About the Author
Thursday, February 16, 2006
Mesothelioma - Asbestos In My Body?
Mesothelioma-Asbestos In My Body? by P Hope
Mesothelioma is a cancer which is linked to exposure to asbestos fibers in 70 to 80 percent of cases. The National Cancer institute defines malignant mesothelioma as "a rare form of cancer...a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)." It is one of the most deadly cancers known to man; the average life span of an afflicted person from the time of diagnosis until death is less than 24 months.
Mesothelioma developes in approximately 3,000 United States citizens every year. Most of those diagnosed have a history of occupational exposure to asbestos, though a few have environmental or household contact. This cancer has an extremely long latency period; an exposure period of as little as one or two months can result in a mesothelioma up to 50 years later. Patients who had contact with asbestos as far back as the 1940s are now being diagnosed with this disease. In fact, the average time between exposure and the development of mesothelioma is 35-40 years.
When asbestos first came into use, its risks were unknown, and it was widely used as a fire-retardant material. Many people worked with this deadly substance, unaware that it would kill them several decades later. Workers such as bricklayers, insulaters, plasterers, electricians, mechanics, carpenters, and other tradesmen were exposed to asbestos on a daily basis as it was contained in many insulation and construction materials.
Even occassional exposure to asbestos is a health risk, and there have been many cases of mesothelioma developing in patients who only had brief contact, such as wives of asbestos-exposed workers who washed their husbands' overalls.
Due to the long latency period and vague, diffuse initial symptoms, there is often a delay in accurate diagnosis. As with many cancers, early symptoms can be mild and non-specific. Often patients present with only shortness of breath and a persistent cough; some show no symptoms at all in the initial stages, and the disease is first noticed on a routine chest X-ray. One early tell-tale sign is pleural effusion, a collection of fluid in the lungs. The right lung is affected 60% of the time, bilateral involvement being seen in 5% of cases. Less common initial complaints due to lung mesothelioma are fever, night sweats, weight loss, a raspy voice and facial swelling. Peritoneal mesothelioma can cause abdominal symptoms such as pain, abdominal swelling, nausea, weight loss, bowel obstruction, anemia and swelling of the feet. As the disease progresses, patients often develop severe cachexia (wasting).
One of the most common symptoms of mesothelioma, pleural effusion, is an accumulation of fluid between the parietal pleura, which covers the chest wall and diaphragm, and the visceral pleura, which covers the lungs. Both membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is removed via blood and lymph vessels, thus maintaining a balance. When more fluid is produced than can be absorbed, an effusion forms.
These effusions are called either transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. Often this is caused by congestive heart failure. An exudate, which contains many cells and proteins and is often cloudy in color, results from disease of the pleura itself, and is common to mesothelioma. To differentiate between a transudate or an exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
As the volume of excess fluid increases, symptoms develop such as shortness of breath (dyspnea) , chest pain, or a non-productive dry cough. Heard through a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
A pleural effusion can be seen with a chest X-ray, ultrasound or CT scan. Since pleural effusions are often caused by congestive heart failure, the discovery of an effusion is not in itself immediately suggestive of a malignant process.
A histological examination of pleural fluid is negative in 85% of cases; a definitive diagnoses is more often is obtained by a needle biopsy or surgical biopsy of pleural tissue.
Symptomatic treatment of lung compression caused by effusion is accomplished by application of a sclerosing agent which eliminates the space between the lung and the chest cavity, a process called chemical pleurodesis. Talc is usually used, with a success rate of 95%. It can be administered either as a powder or as a slurry mixed with saline. A surgical team opens the chest wall, removes the effusion, then collapses the lung before applying the talc. Once the lung is fused to the chest wall, an effusion can no longer accumulate and compress the lung. This is strictly a palliative measure to improve the patient's quality of life, and has no effect on the progression of the disease.
Attemps to cure mesothelioma utilize surgery to remove diseased tissue, combined with chemo and raiotherapy. Several new treatment modalities are currently being investigated. These include Photodynamic therapy, which uses light of particular frequencies to target and kill cancer cells which, compared to normal tissue, display increased uptake of photosensitizing drugs; immunotherapy, which fights the abnormal cells through stimulation of the body's own immune system; and Intensity Modulated Radiation Therapy, which is a radiation treatment that attempts to target just the malignancy, thus avoiding damage to adjacent healthy cells and tissue. In addition, some success has been acheived with the chemotherapeutic drug Alitma (pemetrexed). However, despite the number of clinical trials currently underway, as of the date of this article the prognosis for mesothelioma sufferers is still extremely poor.
Wednesday, February 15, 2006
Asbestos - Can You Sue For Mesothelioma Too?
Asbestos-Can You Sue For MesotheliomaToo? by H Hendricks
Asbestos is a naturally-occuring fibrous mineral of metamorpic hydrous magnesium silicate. The term "metamorphic" is used to describe a process of extreme heat and pressure which creates specific secondary patterns of minerals with new chemical and/or physical properties. As the primary rock is heated and recooled, silicate crystals align in long rows of mineral fibers, which easily separate into tiny shards thinner than a human hair. Asbestos fibers are not a health risk as long as they are undisturbed. However, when asbestos is undergoes natural weathering, or is mined and processed, the microscopic particles waft into the air and cause disease if they are inhaled.
Asbestosis occurs when an inhaled asbestos particle irritates the body's natural defence mechanisms, causing inflammation and scarring which eventually restricts lung function. Mesothelioma is a malignant tumor of the membranes surrounding the heart, lungs and abdominal cavity. Asbestos can also cause cancer of the mouth, throat, esophagus, larynx, stomach, lung and lymphoid tissue.
Asbestos exposure can also cause non-fatal illnesses such as asbestos warts, caused when asbestos fibers are lodged in the skin, causing lumps of scar tissue to form around the irritant in the same manner as they do in the lungs to cause asbestosis; pleural plaques, discrete, sometimes calcified fibrous lesions which can be seen on X-rays but are too small to cause breathing impairment; and diffuse pleural thickening, which can cause breathing impairment if it is extensive.
Due to its fire resistant properties, asbestos has been used historically for household and industrial purposes. It has been found woven into burial cloths in ancient Egypt, and Charlemagne reportedly had a tablecloth made of asbestos which he would throw into a fire to clean.
In World War II asbestos was considered so important by the War Department that it was considered a strategic material, and many American workers were exposed in the World War II boom in shipbuilding. After the war, it was widely used in the construction industry.
In modern Western society, it was used for such diverse purposes as lamp wicks, brake shoes, oven insulation, electrical hotplate wiring and home insulation, roofing and flooring. For instance, some kinds of vermiculite used in home insulation into the 1970s contained asbestos. The EPA banned this product in 1977.
When a home owner discovers asbestos in an old home, it should not be a cause for immediate panic. If the asbestos looks intact and is not pulverized, it is best to leave it alone. However, because of legal liability, schools and businesses containing asbestos usually must undergo a costly removal process, hazardous in itself because disturbing the stable asbestos product causes fibers to fill the air. Special equipment must be used to insure that the removal process does not cause health problems where non existed before.
Most industrialized nations have reduced or banned the use of asbestos for at least 30 years and now use fiberglass or woven ceramic fiber as a substitute, but since asbestos-caused disease has a latency period of up to 50 years, patients are still presenting with these illness today. Every year in America, approximately 3000 new cases of mesothelioma are diagnosed, and 550 deaths occurs due to asbestosis. According to the March 1991 Report of the Judicial Conference Ad Hoc Committee on Asbestos Litigation, asbestos exposure has caused the deaths of approximately 200,000 to 265,000 Americans.
Asbestos use peaked in the United States in 1973, when 1 million tons of the material were used. The EPA attempted to institute a complete legal ban on the use of asbestos products in 1989; however, this ban was largely eviscerated by the US 5th Circuit Court of Appeals in 1991, and some restricted use of asbestos, albeit in fewer products than than before, resumed. Therefor, even today some workers are being exposed to this toxic material.
Asbestos is a serious continuing concern to the Environmental Protection Agency, and their website has detailed information on asbestos and its removal.
Concerns about the health risks of asbestos exposure date back to 1898, when the Chief Inspector of Factories of the United Kingdom reported to Parliament in his Annual Report about the "evil effects of asbestos dust". He noted that the "sharp, glass like nature of the particles" when allowed to remain suspended in the air, "have been found to be injurious, as might have been expected". In 1906 a British Parliamentary Commission confirmed the first cases of asbestos-related deaths in Bristish factories and called for improved ventilation and other safety measures. In 1918 an American insurance company produced a study showing premature deaths in the asbestos industry in the United States and in 1926 the Massachusetts Industrial Accidents Board processed the first successful compensation claim by a sick asbestos worker.
Today, lawsuits claiming compensation for asbestos-related illnesses are a growth industry in the legal profession. An internet search of "mesothelioma lawyer" yields 1,910,000 results. The original manufacturers of asbestos products have long since been driven into Chapter 11 bankruptcy; plaintiffs have now turned to suing corporations with peripheral connections to asbestos products. More than 70 American corporations have filed Chapter 11 bankruptcy in due to asbestos liability claims.
Since the 1970's, approximateley 6% of all lawsuits filed in American courts have been asbestos-related. The lawsuits now facing the courts have been described as "an elephantine mass" by the US Supreme Court, and are expected to cost between 200 to 275 billion dollars to settle. Asbestos liability is one of the largest issues facing the global insurance industry today.
Most epidemiological studies expected the number of lawsuits to peak in the 1990s, but this has not occurred, either because of the long latency period of asbestos-related diseases, or because legal action is becoming more popular among asbestos-exposed members of the public due to high-profile legal cases and widespread advertising by attorneys who specialize in such cases.
Many complaints have been made by representatives of industries facing lawsuits and the insurance companies who will be expected to pay them that the asbestos-lawsuit industry is rife with fraud, with less that half of all payouts reaching the plaintiffs. Aggressive, ambulance-chasing lawyers are said to exaggerate medical disability and coach clients on their testimony.
The group of plaintiffs includes not only ill people, but also those who have merely have a history of asbestos exposure and want compensation for potential future health risks. According to the American Academy of Acturaries Mass Tort Work Group, more than 100 million Americans have been exposed to asbestos in their workplace during the past century.
Monday, February 13, 2006
Mesothelioma Is An Incurable Cancer That Makes Lawyers Rich
Mesothelioma Is An Incurable Cancer That Makes Lawyers Rich by frank vanderlugt
Mesothelioma is a cancer which is linked to exposure to asbestos fibers in 70 to 80 percent of cases.
The National Cancer institute defines malignant mesothelioma as "a rare form of cancer...a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)."
It is one of the most deadly cancers known to man; the average life span of an afflicted person from the time of diagnosis until death is less than 24 months.
Mesothelioma develops in approximately 3,000 United States citizens every year. Most of those diagnosed have a history of occupational exposure to asbestos, though a few have environmental or household contact. This cancer has an extremely long latency period; an exposure period of as little as one or two months can result in a mesothelioma up to 50 years later. Patients who had contact with asbestos as far back as the 1940s are now being diagnosed with this disease. In fact, the average time between exposure and the development of mesothelioma is 35-40 years.
When asbestos first came into use, its risks were unknown, and it was widely used as a fire-retardant material. Many people worked with this deadly substance, unaware that it would kill them several decades later. Workers such as bricklayers, insulaters, plasterers, electricians, mechanics, carpenters, and other tradesmen were exposed to asbestos on a daily basis as it was contained in many insulation and construction materials.
Even occassional exposure to asbestos is a health risk, and there have been many cases of mesothelioma developing in patients who only had brief contact, such as wives of asbestos-exposed workers who washed their husbands' overalls.
Due to the long latency period and vague, diffuse initial symptoms, there is often a delay in accurate diagnosis. As with many cancers, early symptoms can be mild and non-specific. Often patients present with only shortness of breath and a persistent cough; some show no symptoms at all in the initial stages, and the disease is first noticed on a routine chest X-ray. One early tell-tale sign is pleural effusion, a collection of fluid in the lungs. The right lung is affected 60% of the time, bilateral involvement being seen in 5% of cases. Less common initial complaints due to lung mesothelioma are fever, night sweats, weight loss, a raspy voice and facial swelling. Peritoneal mesothelioma can cause abdominal symptoms such as pain, abdominal swelling, nausea, weight loss, bowel obstruction, anemia and swelling of the feet. As the disease progresses, patients often develop severe cachexia (wasting).
One of the most common symptoms of mesothelioma, pleural effusion, is an accumulation of fluid between the parietal pleura, which covers the chest wall and diaphragm, and the visceral pleura, which covers the lungs. Both membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is removed via blood and lymph vessels, thus maintaining a balance. When more fluid is produced than can be absorbed, an effusion forms.
These effusions are called either transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. Often this is caused by congestive heart failure. An exudate, which contains many cells and proteins and is often cloudy in color, results from disease of the pleura itself, and is common to mesothelioma. To differentiate between a transudate or an exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
As the volume of excess fluid increases, symptoms develop such as shortness of breath (dyspnea) , chest pain, or a non-productive dry cough. Heard through a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
A pleural effusion can be seen with a chest X-ray, ultrasound or CT scan. Since pleural effusions are often caused by congestive heart failure, the discovery of an effusion is not in itself immediately suggestive of a malignant process.
A histological examination of pleural fluid is negative in 85% of cases; a definitive diagnoses is more often is obtained by a needle biopsy or surgical biopsy of pleural tissue.
Symptomatic treatment of lung compression caused by effusion is accomplished by application of a sclerosing agent which eliminates the space between the lung and the chest cavity, a process called chemical pleurodesis. Talc is usually used, with a success rate of 95%. It can be administered either as a powder or as a slurry mixed with saline. A surgical team opens the chest wall, removes the effusion, then collapses the lung before applying the talc. Once the lung is fused to the chest wall, an effusion can no longer accumulate and compress the lung. This is strictly a palliative measure to improve the patient's quality of life, and has no effect on the progression of the disease.
Attemps to cure mesothelioma utilize surgery to remove diseased tissue, combined with chemo and raiotherapy. Several new treatment modalities are currently being investigated. These include Photodynamic therapy, which uses light of particular frequencies to target and kill cancer cells which, compared to normal tissue, display increased uptake of photosensitizing drugs; immunotherapy, which fights the abnormal cells through stimulation of the body's own immune system; and Intensity Modulated Radiation Therapy, which is a radiation treatment that attempts to target just the malignancy, thus avoiding damage to adjacent healthy cells and tissue. In addition, some success has been acheived with the chemotherapeutic drug Alitma (pemetrexed). However, despite the number of clinical trials currently underway, as of the date of this article the prognosis for mesothelioma sufferers is still extremely poor.
About the Author
Frank Vanderlugt is interested in Mesothelioma Life Extension Anxiety
Friday, February 10, 2006
Malignant Mesothelioma
Mesothelioma by Astron
Malignant mesothelioma is an uncommon, but no longer rare, cancer that is difficult to diagnose and poorly responsive to therapy. Malignant mesothelioma is the most serious of all asbestos-related diseases. A layer of specialized cells called mesothelial cells lines the chest cavity, abdominal cavity, and the cavity around the heart. These cells also cover the outer surface of most internal organs. The tissue formed by these cells is called mesothelium.
The mesothelium helps protect the organs by producing a special lubricating fluid that allows organs to move around. For example, this fluid makes it easier for the lungs to move inside the chest during breathing. The mesothelium of the chest is called the pleura and the mesothelium of the abdomen is known as the peritoneum. The mesothelium of the pericardial cavity (the "sac-like" space around the heart) is called the pericardium
Tumors of the mesothelium can be benign (noncancerous) or malignant (cancerous). A malignant tumor of the mesothelium is called a malignant mesothelioma. Because most mesothelial tumors are cancerous, malignant mesothelioma is often simply called mesothelioma. Mesothelioma was recognized as a tumor of the pleura, peritoneum and pericardium in the late 1700's. However it was not until much later, in 1960, that this particular type of tumor was described in more detail and even more importantly, its association with asbestos exposure was recognized. The first report linking mesothelioma to asbestos exposure was written by J.C.Wagner, and described 32 cases of workers in the "Asbestos Hills" in South Africa. Since than the relationship between mesothelioma and asbestos exposure has been confirmed in studies around the world.
The incidence of mesothelioma in the United States remains very low, with 14 cases occurring per million people per year. Despite these numbers the noticed threefold increase in mesothelioma in males between 1970 and 1984, is directly associated with environmental and occupational exposure to asbestos, mostly in areas of asbestos product plants and shipbuilding facilities. Although the disease is much more commonly seen in 60-year old men, it has been described in women and early childhood as well. The cause of the disease is not so well understood in these latter two groups, but there is some evidence of possible asbestos exposure for some of these cases as well
Mesothelioma is one of the deadliest diseases known to man; the average life span of an inflicted person from the time of diagnosis until death is less than 24 months. It's a disease that strikes approximately 3,000 United States citizens each and every year; hard working people who have labored for a lifetime to provide for their families, doing the work that keeps this country running and a great place to live. They worked in factories, at shipyards, in mines, for the US military, as engineers, as pipefitters, as steel workers, as auto mechanics, and in so many other professions. They came home to their loved ones exhausted and covered in dirt and dust; tired, but content that they had a job and were providing for their family. Content that they were putting food on the table and a house over their loved one's heads. Content that they were working to make a better life for their families in this generation and the next... But what they didn't know was that while they were working so hard, they were not only slowly killing themselves, but those that they were working so hard to help; their family, their loved ones.
What is the mesothelium? The mesothelium is a membrane that covers and protects most of the internal organs of the body. It is composed of two layers of cells: One layer immediately surrounds the organ; the other forms a sac around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing moving organs (such as the beating heart and the expanding and contracting lungs) to glide easily against adjacent structures. The mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women
What Is My Diagnosis? There are three types of mesothelioma. Pleural mesothelioma is a cancer of the lining of the lung (pleura), peritoneal mesothelioma is a cancer of the lining of the abdominal cavity (peritoneum), and pericardial mesothelioma is a cancer of the lining surrounding the heart (pericardium). Sub-types (or cell types) of mesothelioma are epithelioid (the most common, and considered the most amenable to treatment), sarcomatous (a much more aggressive form), and biphasic or mixed (a combination of both of the other cell types). The structural appearance of cells under the microscope determine the cell or sub-type of mesothelioma. Epithelioid is the least aggressive; sarcomatoid, the most aggressive. The biphasic or mixed cell type shows structural elements of both of the other two.
About the Author
Malignant mesothelioma is an uncommon, but no longer rare, cancer that is difficult to diagnose and poorly responsive to therapy. Malignant mesothelioma is the most serious of all asbestos-related diseases.
For additional pictures and information, click here or on the picture below
What is Mesothelioma (Asbestos Cancer)?
It is a form of cancer in which malignant (cancerous) cells are found in the mesothelium which is a protective sac that covers most of the body's internal organs. Generally, most individuals who develop this cancer have worked on jobs or lived in apartments or buildings where asbestos particles were inhaled.
Asbestos cancer is when the mesothelium lining becomes abnormal and grows uncontrollably causing pain. This can be benign or malignant. The malignant form of the cancer will damage the tissue of the organ it resides on and possibly invade other organs. Most cases of mesothelioma are either pleural or peritoneal. the Most cases of begin in the pleura or peritoneum.
Mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women.
This site is dedicated to providing advice that can help those with questions concerning asbestos cancer.
Sunday, February 19, 2006
Pericardial Mesothelioma Treatment
Pericardial Mesothelioma Treatment by William Johnston
Pericardial Mesothelioma is an extremely difficult cancer to treat and presently, all treatment methods used have a poor success rate. The chances of a patient's survival depend largely on how early and how aggressively the cancer is treated. If pericardial mesothelioma is treated when it has fully matured and developed then the chances of survival are very slim and the prognosis for a patient could be only a couple of months. The latency period of pericardial mesothelioma (30 - 50 years), and its symptoms which are ordinary of other more common diseases such as pneumonia, make it extremely difficult to diagnose and therefore difficult to treat in its early stages. In this way, a lot of pericardial mesothelioma treatments do not aim to cure patients but instead focus on reducing the symptoms.
Before a patient is treated, a doctor will evaluate him or her, and afterwards decide which treatment method is most suitable for the patient's situation. The patient's age, medical history, general well being and even weight are taken into account before the doctor will decide which of the three treatments are most appropriate. These treatments are surgery, chemotherapy and radiation therapy.
Surgery
There are two different types of surgery that can be used one of which is called aggressive surgery. This is the most dangerous of all the treatment methods available and only the fittest of people are deemed strong enough to undergo this. Aggressive surgery consists of removing large chunks of cancerous cells from inside the patient. This is extremely dangerous in the case of pericardial mesothelioma seeing as the cancerous cells are in extremely close proximity to vital organs such as the heart and lungs. Extremely skilled surgeons are needed to perform this operation.
The second type of surgery is palliative procedures and this type of surgery is used only for the purpose of reducing the symptoms of the cancer. Palliative procedures are performed when pericardial mesothelioma is in its latest stages and is practically impossible to cure.
Chemotherapy
Chemotherapy is the most well known cure of cancers and involves using drugs to kill of cancerous cells. However, many of the drugs used do not have a high success rate although researchers are discovering new combinations of drugs that work more effectively. Many pharmaceutical companies are also endeavouring to find new drugs. Researchers predict that they will soon discover a drug with a significantly improved success rate.
Radiation Therapy
This form of treatment uses doses of radiation to kill cancerous cells. However, in the case of pericardial mesothelioma this is extremely difficult because as well as damaging cancerous cells, the radiation also damages vital organs such as the heart and lungs. This makes using radiation therapy most effectively extremely difficult. The dose of radiation is usually too weak to make a significant impact on curing pericardial mesothelioma.
Dual Therapy
Dual therapy is just a combination of surgery, chemotherapy and radiation therapy. This consists of using surgery to remove the majority of the cancer cells and then using chemotherapy and radiation therapy to kill off any remaining cells. This has proved to be an effective treatment method however also very dangerous. Only the fittest young people are able to undergo this treatment.
About the Author
Thursday, February 16, 2006
Mesothelioma - Asbestos In My Body?
Mesothelioma-Asbestos In My Body? by P Hope
Mesothelioma is a cancer which is linked to exposure to asbestos fibers in 70 to 80 percent of cases. The National Cancer institute defines malignant mesothelioma as "a rare form of cancer...a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)." It is one of the most deadly cancers known to man; the average life span of an afflicted person from the time of diagnosis until death is less than 24 months.
Mesothelioma developes in approximately 3,000 United States citizens every year. Most of those diagnosed have a history of occupational exposure to asbestos, though a few have environmental or household contact. This cancer has an extremely long latency period; an exposure period of as little as one or two months can result in a mesothelioma up to 50 years later. Patients who had contact with asbestos as far back as the 1940s are now being diagnosed with this disease. In fact, the average time between exposure and the development of mesothelioma is 35-40 years.
When asbestos first came into use, its risks were unknown, and it was widely used as a fire-retardant material. Many people worked with this deadly substance, unaware that it would kill them several decades later. Workers such as bricklayers, insulaters, plasterers, electricians, mechanics, carpenters, and other tradesmen were exposed to asbestos on a daily basis as it was contained in many insulation and construction materials.
Even occassional exposure to asbestos is a health risk, and there have been many cases of mesothelioma developing in patients who only had brief contact, such as wives of asbestos-exposed workers who washed their husbands' overalls.
Due to the long latency period and vague, diffuse initial symptoms, there is often a delay in accurate diagnosis. As with many cancers, early symptoms can be mild and non-specific. Often patients present with only shortness of breath and a persistent cough; some show no symptoms at all in the initial stages, and the disease is first noticed on a routine chest X-ray. One early tell-tale sign is pleural effusion, a collection of fluid in the lungs. The right lung is affected 60% of the time, bilateral involvement being seen in 5% of cases. Less common initial complaints due to lung mesothelioma are fever, night sweats, weight loss, a raspy voice and facial swelling. Peritoneal mesothelioma can cause abdominal symptoms such as pain, abdominal swelling, nausea, weight loss, bowel obstruction, anemia and swelling of the feet. As the disease progresses, patients often develop severe cachexia (wasting).
One of the most common symptoms of mesothelioma, pleural effusion, is an accumulation of fluid between the parietal pleura, which covers the chest wall and diaphragm, and the visceral pleura, which covers the lungs. Both membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is removed via blood and lymph vessels, thus maintaining a balance. When more fluid is produced than can be absorbed, an effusion forms.
These effusions are called either transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. Often this is caused by congestive heart failure. An exudate, which contains many cells and proteins and is often cloudy in color, results from disease of the pleura itself, and is common to mesothelioma. To differentiate between a transudate or an exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
As the volume of excess fluid increases, symptoms develop such as shortness of breath (dyspnea) , chest pain, or a non-productive dry cough. Heard through a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
A pleural effusion can be seen with a chest X-ray, ultrasound or CT scan. Since pleural effusions are often caused by congestive heart failure, the discovery of an effusion is not in itself immediately suggestive of a malignant process.
A histological examination of pleural fluid is negative in 85% of cases; a definitive diagnoses is more often is obtained by a needle biopsy or surgical biopsy of pleural tissue.
Symptomatic treatment of lung compression caused by effusion is accomplished by application of a sclerosing agent which eliminates the space between the lung and the chest cavity, a process called chemical pleurodesis. Talc is usually used, with a success rate of 95%. It can be administered either as a powder or as a slurry mixed with saline. A surgical team opens the chest wall, removes the effusion, then collapses the lung before applying the talc. Once the lung is fused to the chest wall, an effusion can no longer accumulate and compress the lung. This is strictly a palliative measure to improve the patient's quality of life, and has no effect on the progression of the disease.
Attemps to cure mesothelioma utilize surgery to remove diseased tissue, combined with chemo and raiotherapy. Several new treatment modalities are currently being investigated. These include Photodynamic therapy, which uses light of particular frequencies to target and kill cancer cells which, compared to normal tissue, display increased uptake of photosensitizing drugs; immunotherapy, which fights the abnormal cells through stimulation of the body's own immune system; and Intensity Modulated Radiation Therapy, which is a radiation treatment that attempts to target just the malignancy, thus avoiding damage to adjacent healthy cells and tissue. In addition, some success has been acheived with the chemotherapeutic drug Alitma (pemetrexed). However, despite the number of clinical trials currently underway, as of the date of this article the prognosis for mesothelioma sufferers is still extremely poor.
Wednesday, February 15, 2006
Asbestos - Can You Sue For Mesothelioma Too?
Asbestos-Can You Sue For MesotheliomaToo? by H Hendricks
Asbestos is a naturally-occuring fibrous mineral of metamorpic hydrous magnesium silicate. The term "metamorphic" is used to describe a process of extreme heat and pressure which creates specific secondary patterns of minerals with new chemical and/or physical properties. As the primary rock is heated and recooled, silicate crystals align in long rows of mineral fibers, which easily separate into tiny shards thinner than a human hair. Asbestos fibers are not a health risk as long as they are undisturbed. However, when asbestos is undergoes natural weathering, or is mined and processed, the microscopic particles waft into the air and cause disease if they are inhaled.
Asbestosis occurs when an inhaled asbestos particle irritates the body's natural defence mechanisms, causing inflammation and scarring which eventually restricts lung function. Mesothelioma is a malignant tumor of the membranes surrounding the heart, lungs and abdominal cavity. Asbestos can also cause cancer of the mouth, throat, esophagus, larynx, stomach, lung and lymphoid tissue.
Asbestos exposure can also cause non-fatal illnesses such as asbestos warts, caused when asbestos fibers are lodged in the skin, causing lumps of scar tissue to form around the irritant in the same manner as they do in the lungs to cause asbestosis; pleural plaques, discrete, sometimes calcified fibrous lesions which can be seen on X-rays but are too small to cause breathing impairment; and diffuse pleural thickening, which can cause breathing impairment if it is extensive.
Due to its fire resistant properties, asbestos has been used historically for household and industrial purposes. It has been found woven into burial cloths in ancient Egypt, and Charlemagne reportedly had a tablecloth made of asbestos which he would throw into a fire to clean.
In World War II asbestos was considered so important by the War Department that it was considered a strategic material, and many American workers were exposed in the World War II boom in shipbuilding. After the war, it was widely used in the construction industry.
In modern Western society, it was used for such diverse purposes as lamp wicks, brake shoes, oven insulation, electrical hotplate wiring and home insulation, roofing and flooring. For instance, some kinds of vermiculite used in home insulation into the 1970s contained asbestos. The EPA banned this product in 1977.
When a home owner discovers asbestos in an old home, it should not be a cause for immediate panic. If the asbestos looks intact and is not pulverized, it is best to leave it alone. However, because of legal liability, schools and businesses containing asbestos usually must undergo a costly removal process, hazardous in itself because disturbing the stable asbestos product causes fibers to fill the air. Special equipment must be used to insure that the removal process does not cause health problems where non existed before.
Most industrialized nations have reduced or banned the use of asbestos for at least 30 years and now use fiberglass or woven ceramic fiber as a substitute, but since asbestos-caused disease has a latency period of up to 50 years, patients are still presenting with these illness today. Every year in America, approximately 3000 new cases of mesothelioma are diagnosed, and 550 deaths occurs due to asbestosis. According to the March 1991 Report of the Judicial Conference Ad Hoc Committee on Asbestos Litigation, asbestos exposure has caused the deaths of approximately 200,000 to 265,000 Americans.
Asbestos use peaked in the United States in 1973, when 1 million tons of the material were used. The EPA attempted to institute a complete legal ban on the use of asbestos products in 1989; however, this ban was largely eviscerated by the US 5th Circuit Court of Appeals in 1991, and some restricted use of asbestos, albeit in fewer products than than before, resumed. Therefor, even today some workers are being exposed to this toxic material.
Asbestos is a serious continuing concern to the Environmental Protection Agency, and their website has detailed information on asbestos and its removal.
Concerns about the health risks of asbestos exposure date back to 1898, when the Chief Inspector of Factories of the United Kingdom reported to Parliament in his Annual Report about the "evil effects of asbestos dust". He noted that the "sharp, glass like nature of the particles" when allowed to remain suspended in the air, "have been found to be injurious, as might have been expected". In 1906 a British Parliamentary Commission confirmed the first cases of asbestos-related deaths in Bristish factories and called for improved ventilation and other safety measures. In 1918 an American insurance company produced a study showing premature deaths in the asbestos industry in the United States and in 1926 the Massachusetts Industrial Accidents Board processed the first successful compensation claim by a sick asbestos worker.
Today, lawsuits claiming compensation for asbestos-related illnesses are a growth industry in the legal profession. An internet search of "mesothelioma lawyer" yields 1,910,000 results. The original manufacturers of asbestos products have long since been driven into Chapter 11 bankruptcy; plaintiffs have now turned to suing corporations with peripheral connections to asbestos products. More than 70 American corporations have filed Chapter 11 bankruptcy in due to asbestos liability claims.
Since the 1970's, approximateley 6% of all lawsuits filed in American courts have been asbestos-related. The lawsuits now facing the courts have been described as "an elephantine mass" by the US Supreme Court, and are expected to cost between 200 to 275 billion dollars to settle. Asbestos liability is one of the largest issues facing the global insurance industry today.
Most epidemiological studies expected the number of lawsuits to peak in the 1990s, but this has not occurred, either because of the long latency period of asbestos-related diseases, or because legal action is becoming more popular among asbestos-exposed members of the public due to high-profile legal cases and widespread advertising by attorneys who specialize in such cases.
Many complaints have been made by representatives of industries facing lawsuits and the insurance companies who will be expected to pay them that the asbestos-lawsuit industry is rife with fraud, with less that half of all payouts reaching the plaintiffs. Aggressive, ambulance-chasing lawyers are said to exaggerate medical disability and coach clients on their testimony.
The group of plaintiffs includes not only ill people, but also those who have merely have a history of asbestos exposure and want compensation for potential future health risks. According to the American Academy of Acturaries Mass Tort Work Group, more than 100 million Americans have been exposed to asbestos in their workplace during the past century.
Monday, February 13, 2006
Mesothelioma Is An Incurable Cancer That Makes Lawyers Rich
Mesothelioma Is An Incurable Cancer That Makes Lawyers Rich by frank vanderlugt
Mesothelioma is a cancer which is linked to exposure to asbestos fibers in 70 to 80 percent of cases.
The National Cancer institute defines malignant mesothelioma as "a rare form of cancer...a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)."
It is one of the most deadly cancers known to man; the average life span of an afflicted person from the time of diagnosis until death is less than 24 months.
Mesothelioma develops in approximately 3,000 United States citizens every year. Most of those diagnosed have a history of occupational exposure to asbestos, though a few have environmental or household contact. This cancer has an extremely long latency period; an exposure period of as little as one or two months can result in a mesothelioma up to 50 years later. Patients who had contact with asbestos as far back as the 1940s are now being diagnosed with this disease. In fact, the average time between exposure and the development of mesothelioma is 35-40 years.
When asbestos first came into use, its risks were unknown, and it was widely used as a fire-retardant material. Many people worked with this deadly substance, unaware that it would kill them several decades later. Workers such as bricklayers, insulaters, plasterers, electricians, mechanics, carpenters, and other tradesmen were exposed to asbestos on a daily basis as it was contained in many insulation and construction materials.
Even occassional exposure to asbestos is a health risk, and there have been many cases of mesothelioma developing in patients who only had brief contact, such as wives of asbestos-exposed workers who washed their husbands' overalls.
Due to the long latency period and vague, diffuse initial symptoms, there is often a delay in accurate diagnosis. As with many cancers, early symptoms can be mild and non-specific. Often patients present with only shortness of breath and a persistent cough; some show no symptoms at all in the initial stages, and the disease is first noticed on a routine chest X-ray. One early tell-tale sign is pleural effusion, a collection of fluid in the lungs. The right lung is affected 60% of the time, bilateral involvement being seen in 5% of cases. Less common initial complaints due to lung mesothelioma are fever, night sweats, weight loss, a raspy voice and facial swelling. Peritoneal mesothelioma can cause abdominal symptoms such as pain, abdominal swelling, nausea, weight loss, bowel obstruction, anemia and swelling of the feet. As the disease progresses, patients often develop severe cachexia (wasting).
One of the most common symptoms of mesothelioma, pleural effusion, is an accumulation of fluid between the parietal pleura, which covers the chest wall and diaphragm, and the visceral pleura, which covers the lungs. Both membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is removed via blood and lymph vessels, thus maintaining a balance. When more fluid is produced than can be absorbed, an effusion forms.
These effusions are called either transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. Often this is caused by congestive heart failure. An exudate, which contains many cells and proteins and is often cloudy in color, results from disease of the pleura itself, and is common to mesothelioma. To differentiate between a transudate or an exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
As the volume of excess fluid increases, symptoms develop such as shortness of breath (dyspnea) , chest pain, or a non-productive dry cough. Heard through a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
A pleural effusion can be seen with a chest X-ray, ultrasound or CT scan. Since pleural effusions are often caused by congestive heart failure, the discovery of an effusion is not in itself immediately suggestive of a malignant process.
A histological examination of pleural fluid is negative in 85% of cases; a definitive diagnoses is more often is obtained by a needle biopsy or surgical biopsy of pleural tissue.
Symptomatic treatment of lung compression caused by effusion is accomplished by application of a sclerosing agent which eliminates the space between the lung and the chest cavity, a process called chemical pleurodesis. Talc is usually used, with a success rate of 95%. It can be administered either as a powder or as a slurry mixed with saline. A surgical team opens the chest wall, removes the effusion, then collapses the lung before applying the talc. Once the lung is fused to the chest wall, an effusion can no longer accumulate and compress the lung. This is strictly a palliative measure to improve the patient's quality of life, and has no effect on the progression of the disease.
Attemps to cure mesothelioma utilize surgery to remove diseased tissue, combined with chemo and raiotherapy. Several new treatment modalities are currently being investigated. These include Photodynamic therapy, which uses light of particular frequencies to target and kill cancer cells which, compared to normal tissue, display increased uptake of photosensitizing drugs; immunotherapy, which fights the abnormal cells through stimulation of the body's own immune system; and Intensity Modulated Radiation Therapy, which is a radiation treatment that attempts to target just the malignancy, thus avoiding damage to adjacent healthy cells and tissue. In addition, some success has been acheived with the chemotherapeutic drug Alitma (pemetrexed). However, despite the number of clinical trials currently underway, as of the date of this article the prognosis for mesothelioma sufferers is still extremely poor.
About the Author
Frank Vanderlugt is interested in Mesothelioma Life Extension Anxiety
Friday, February 10, 2006
Malignant Mesothelioma
Mesothelioma by Astron
Malignant mesothelioma is an uncommon, but no longer rare, cancer that is difficult to diagnose and poorly responsive to therapy. Malignant mesothelioma is the most serious of all asbestos-related diseases. A layer of specialized cells called mesothelial cells lines the chest cavity, abdominal cavity, and the cavity around the heart. These cells also cover the outer surface of most internal organs. The tissue formed by these cells is called mesothelium.
The mesothelium helps protect the organs by producing a special lubricating fluid that allows organs to move around. For example, this fluid makes it easier for the lungs to move inside the chest during breathing. The mesothelium of the chest is called the pleura and the mesothelium of the abdomen is known as the peritoneum. The mesothelium of the pericardial cavity (the "sac-like" space around the heart) is called the pericardium
Tumors of the mesothelium can be benign (noncancerous) or malignant (cancerous). A malignant tumor of the mesothelium is called a malignant mesothelioma. Because most mesothelial tumors are cancerous, malignant mesothelioma is often simply called mesothelioma. Mesothelioma was recognized as a tumor of the pleura, peritoneum and pericardium in the late 1700's. However it was not until much later, in 1960, that this particular type of tumor was described in more detail and even more importantly, its association with asbestos exposure was recognized. The first report linking mesothelioma to asbestos exposure was written by J.C.Wagner, and described 32 cases of workers in the "Asbestos Hills" in South Africa. Since than the relationship between mesothelioma and asbestos exposure has been confirmed in studies around the world.
The incidence of mesothelioma in the United States remains very low, with 14 cases occurring per million people per year. Despite these numbers the noticed threefold increase in mesothelioma in males between 1970 and 1984, is directly associated with environmental and occupational exposure to asbestos, mostly in areas of asbestos product plants and shipbuilding facilities. Although the disease is much more commonly seen in 60-year old men, it has been described in women and early childhood as well. The cause of the disease is not so well understood in these latter two groups, but there is some evidence of possible asbestos exposure for some of these cases as well
Mesothelioma is one of the deadliest diseases known to man; the average life span of an inflicted person from the time of diagnosis until death is less than 24 months. It's a disease that strikes approximately 3,000 United States citizens each and every year; hard working people who have labored for a lifetime to provide for their families, doing the work that keeps this country running and a great place to live. They worked in factories, at shipyards, in mines, for the US military, as engineers, as pipefitters, as steel workers, as auto mechanics, and in so many other professions. They came home to their loved ones exhausted and covered in dirt and dust; tired, but content that they had a job and were providing for their family. Content that they were putting food on the table and a house over their loved one's heads. Content that they were working to make a better life for their families in this generation and the next... But what they didn't know was that while they were working so hard, they were not only slowly killing themselves, but those that they were working so hard to help; their family, their loved ones.
What is the mesothelium? The mesothelium is a membrane that covers and protects most of the internal organs of the body. It is composed of two layers of cells: One layer immediately surrounds the organ; the other forms a sac around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing moving organs (such as the beating heart and the expanding and contracting lungs) to glide easily against adjacent structures. The mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women
What Is My Diagnosis? There are three types of mesothelioma. Pleural mesothelioma is a cancer of the lining of the lung (pleura), peritoneal mesothelioma is a cancer of the lining of the abdominal cavity (peritoneum), and pericardial mesothelioma is a cancer of the lining surrounding the heart (pericardium). Sub-types (or cell types) of mesothelioma are epithelioid (the most common, and considered the most amenable to treatment), sarcomatous (a much more aggressive form), and biphasic or mixed (a combination of both of the other cell types). The structural appearance of cells under the microscope determine the cell or sub-type of mesothelioma. Epithelioid is the least aggressive; sarcomatoid, the most aggressive. The biphasic or mixed cell type shows structural elements of both of the other two.
About the Author
Malignant mesothelioma is an uncommon, but no longer rare, cancer that is difficult to diagnose and poorly responsive to therapy. Malignant mesothelioma is the most serious of all asbestos-related diseases.
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